Causes of liver failure are numerous. The liver’s failure to perform its normal role can have devastating or fatal consequences.
Acute Liver Failure
Acute liver failure refers to the rapid onset of liver dysfunction in a patient without chronic liver disease.
Acute Alcoholic Hepatitis and Alcohol-Induced Liver Decompensation (AILD)
AILD is a life-threatening form of acute liver failure precipitated by the recent ingestion of alcohol. One common form of AILD is severe acute alcoholic hepatitis (sAAH).
Fulminant Hepatic Failure (FHF)
A relatively rare condition characterized by a rapid deterioration of liver function with altered mental state and coagulopathy. It occurs in individuals without known pre-existing liver disease.
Surgery-Induced Liver Failure (SILF)
Another form of acute liver failure is SILF, which is comprised of Primary Graft Non-Function, Small-For-Size or Split Liver Transplant & Other Forms of Surgery-Induced Liver Failure
Chronic Liver Failure
Chronic liver failure refers to a gradual loss of liver function and is usually characterized by the presence of widespread cirrhosis.
Limitations of Currently Available Treatment Options for Acute Liver Failure
Given the liver’s complexity, there are no simple or widely effective medical solutions to acute liver failure. The only long-term cure for acute liver failure is surgical transplantation.